Dr. Md. Firoz Kabir

Assistant Professor
Biochemistry and Biotechnology
Email: firozkabir@ustc.ac.bd

Profile

I completed a post-doctoral fellowship training at the University of Maryland, Baltimore, MD, USA. Alongside my Ph.D. in molecular biology, I completed pre-doctoral training at Johns Hopkins University, MD, USA. I am skilled in conventional molecular biology laboratory techniques and have extensive experience in handling and maintaining various animal models, including mice, zebrafish, cynomolgus monkeys (Macaca fascicularis), and rabbits. I have cultured multiple cell lines, including RPE-J, human lens epithelial (HLE), Hek293, SH-SY5Y, and corneal endothelial cells. Additionally, I have developed two HLE knock-in cell lines using CRISPR/Cas9 systems. I have performed intravitreal injections on mice. I am skilled in the use of advanced equipment, including electroretinography (ColorDome LabCradle and Celeris, Diagnosys LLC), OptoDrum (Striatech), Spectralis OCT (Heidelberg Engineering), 4D Nucleofector, and the Micron III retinal imaging microscope.
My Presence on Web
PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Firoz+Kabir&sort=date
Google Scholar: ‪‪https://scholar.google.com/citations?hl=en&user=0oeUETkAAAAJ‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬‬

Education

  • Post-Doctoral Fellow, University of Maryland Baltimore, Baltimore, MD, USA (2022-2025).
  • Post-Doctoral Research Fellow, Singapore Eye Research Institute, Singapore (2019-2020).
  • Ph.D. (Molecular Biology), University of the Punjab, Lahore, Pakistan (2018).
  • M.Sc. (Thesis), Genetic Engineering & Biotechnology, University of Rajshahi (2004).
  • B.Sc. (Hons.), Genetics and Breeding, University of Rajshahi (2003).

Program Affiliated

  • B.Sc. (Hons.) in Biochemistry and Biotechnology
  • M.Sc. in Biochemistry and Molecular Biology

Areas of Interest

  • Molecular Biology
  • Human Genetics
  • Ophthalmic Research
  • Cell Biology

Courses Taught

  • BB-413: Immunogenetics
  • B&MB-510 Molecular Diagnostics and Forensic DNA Technology

Journals & Articles

  • Islam, M. A., Hossen, M. B., Horaira, M. A., Hossen, M. A., Kibria, M. K., Reza. M. S., Tuly. K. F., Faruqe, M. O., Kabir, F., Mahumud, R. A., and Mollah, M. N. H. (2023). Exploring Core Genes by Comparative Transcriptomics Analysis for Early Diagnosis, Prognosis, and Therapies of Colorectal Cancer. Cancers (Basel).15(5):1369. PMID: 36900162. IF: 4.5; SJR: Q1.
  • Hossen, M. B., Islam, M. A., Reza, M. S., Kibria, M. K., Horaira, M. A., Tuly, K. F., Faruqe, M. O., Kabir, F., and Mollah, M. N. H. (2023). Robust identification of common genomic biomarkers from multiple gene expression profiles for the prognosis, diagnosis, and therapies of pancreatic cancer. Comput Biol Med. 152:106411. PMID: 36502691. IF: 7; SJR: Q1.
  • Irum, B., Kabir, F., Shoshany, N., Khan, S. Y., Rauf, B., Naeem, M. A., Qaiser, T. A., Riazuddin, S., Hejtmancik, J. F., and Riazuddin, S. A. (2022). A genomic deletion coupled with a fusion of CRYBB2-CRYBB2P1 is responsible for autosomal recessive congenital cataracts. Hum. Genome Var. 9(1):31. PMID: 36075891. IF: 1; SJR: Q3.
  • Khan, S. Y., Ali, M., Kabir, F., Na, C. H., Delannoy, M., Ma, Y., Qiu, C., Costello, M. J., Hejtmancik, J. F. and Riazuddin, S. A. (2022). The role of FYCO1-dependent autophagy in lens fiber cell differentiation. Autophagy. 10.1080/15548627.2022.2025570. PMID: 35343376. IF: 14.6; SJR: Q1
  • Sarkar, M. M. H., Rabbi, M. F. A, Akter, S., Banu, T. A., Goswami, B., Jahan, I., Hossain, M.S., Osman, E., Uzzaman, M. S., Habib, M. A., Mahmud, A. S. M., Kabir, F., Hasan, K. N., Rahman, M. M., Khaleque, M. A., Akhteruzzaman, S., Khan, M. S. (2021). Genome Sequence of a SARS-CoV-2 P.1 Variant of Concern (20J/501Y.V3) from Bangladesh. Microbiol Resour Announc. 10(27): e00524-21. PMID: 34236224. IF: 0.68; SJR: Q3.
  • Ali, M., Khan, S. Y., Rodrigues, T. A., Francisco, T., Jiao, X., Qi, H., Kabir, F., Irum, B., Rauf, B., Khan, A. A., Mehmood, A., Naeem, M. A., Assir, M. Z., Ali, M. H., Shahzad, M., Abu-Amero, K. K., Akram, S. J., Akram, J., Riazuddin, S., Riazuddin, S., Robinson, M. L., Baes, M., Azevedo, J. E., Hejtmancik, J. F., and Riazuddin, S. A. (2021). A missense allele of PEX5 is responsible for the defective import 2 of PTS2 cargo proteins into peroxisomes. Hum Genet. 10.1007/s00439-020-02238-z. PMID: 33389129. IF: 3.8; SJR: Q1.
  • Nadeem, R., Kabir, F., Li, J., Gradstein, L., Jiao, X., Rauf, B., Naeem, M. A., Assir, M. Z., Riazuddin, S., Ayyagari, R., Hejtmancik, J. F., and Riazuddin, S. A. (2020). Mutations in CERKL and RP1 cause Retinitis pigmentosa in Pakistani families. Hum. Genome Var. 7: 14. PMID: 32411380. IF: 1; SJR: Q3.
  • Ali, M., Kabir, F., Raskar, S., Renuse, S., Na, C. H., Delannoy, M., Khan, S. Y., and Riazuddin, S. A. (2020). Generation and Proteome Profiling of PBMC-originated, iPSC-derived Lentoid Bodies. Stem Cell Res. 46:101813. PMID: 32474394. IF: 0.8; SJR: Q4.
  • Rauf, B., Irum, B., Khan, S. Y., Kabir, F., Naeem, M. A., Riazuddin, S., Ayyagari, R., and Riazuddin, S. A. (2020). Novel mutations in LTBP2 identified in familial cases of primary congenital glaucoma. Mol. Vis. 26:14-25. PMID: 32165823. IF: 2.2; SJR: Q2.
  • Ali, M., Kabir, F., Thomson, J. J., Ma, Y., Qiu, C., Delannoy, M., Khan, S. Y., and Riazuddin, S. A. (2019). Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies. Sci. Rep. 9(1):18552. PMID: 31811247. IF: 3.8; SJR: Q1.
  • Khan, S. Y., Kabir, F., M’Hamdi, O., Jiao, X., Naeem, M. A., Khan, S. N., Riazuddin, S., Hejtmancik, J. F. and Riazuddin, S. A. (2018). Whole genome sequencing data for two individuals of Pakistani descent. Sci. Data. 5: 180174. PMID: 30204152. IF: 5.8; SJR: Q1.
  • Ali, M., Khan, S. Y., Kabir, F., Gottsch, J. D. and Riazuddin, S. A. (2018). Comparative transcriptome analysis of hESC- and iPSC-derived corneal endothelial cells. Exp. Eye. Res. S0014-4835(18)30302-6. PMID: 30196069. IF: 3; SJR: Q1.
  • Li, L., Jiao, X., D’Atri, I., Ono, F., Nelson, R., Chan, C. C., Nakaya, N., Ma, Z., Ma, Y., Cai, X., Zhang, L., Lin, S., Hameed, A., Chioza, B. A., Hardy, H., Arno, G., Hull, S., Khan, M. I., Fasham, J., Harlalka, G. V., Michaelides, M., Moore, A. T., Coban Akdemir, Z. H., Jhangiani, S., Lupski, J. R., Cremers, F. P. M., Qamar, R., Salman, A., Chilton, J., Self, J., Ayyagari, R., Kabir, F., Naeem, M. A., Ali, M., Akram, J., Sieving, P. A., Riazuddin, S., Baple, E. L., Riazuddin, S. A., Crosby, A. H. and Hejtmancik, J. F. (2018). Mutation in the intracellular chloride channel CLCC1 associated with autosomal recessive retinitis pigmentosa. PLoS. Genet. 14(8): e1007504. PMID: 30157172. IF: 4; SJR: Q1.
  • Khan, S. Y., Ali, M., Kabir, F., Chen, R., Na, C. H., Lee, M. W., Pourmand, N., Hackett, S. F. and Riazuddin, S. A. (2018). Identification of novel Transcripts and peptides in developing murine lens. Sci. Rep. 8(1): 11162. PMID: 30042402. IF: 3.8; SJR: Q1.
  • Khan, S. Y., Ali, M., Kabir, F., Renuse, S., Na, C. H., Talbot, C. C., Hackett, S. F. and Riazuddin, S. A. (2018). Proteome Profiling of Developing Murine Lens Through Mass Spectrometry. Invest. Ophthalmol. Vis. Sci. 59(1): 100-107. PMID: 29332127. IF: 5; SJR: Q1.
  • Irum, B., Khan, S. Y., Ali, M., Daud, M., Kabir, F., Rauf, B., Fatima, F., Iqbal, H., Khan, A. O., Al, O. S., Naeem, M. A., Nasir, I. A., Khan, S. N., Husnain, T., Riazuddin, S., Akram, J., Eghrari, A. O. and Riazuddin, S. A. (2016). Deletion at the GCNT2 Locus Causes Autosomal Recessive Congenital Cataracts. PLoS. One. 11(12): e0167562. PMID: 27936067. IF: 2.9; SJR: Q1.
  • Ullah, I., Kabir, F., Gottsch, C. B., Naeem, M. A., Guru, A. A., Ayyagari, R., Khan, S. N., Riazuddin, S., Akram, J. and Riazuddin, S. A. (2016). Mutations in phosphodiesterase 6 identified in familial cases of retinitis pigmentosa. Hum. Genome Var. 3: 16036. PMID: 27917291. IF: 1; SJR: Q3.
  • Irum, B., Khan, S. Y., Ali, M., Kaul, H., Kabir, F., Rauf, B., Fatima, F., Nadeem, R., Khan, A. O., Al, O. S., Naeem, M. A., Nasir, I. A., Khan, S. N., Husnain, T., Riazuddin, S., Akram, J., Eghrari, A. O. and Riazuddin, S. A. (2016). Mutation in LIM2 Is Responsible for Autosomal Recessive Congenital Cataracts. PLoS. One. 11(11): e0162620. PMID: 27814360. IF: 2.9; SJR: Q1.
  • Rauf, B., Irum, B., Kabir, F., Firasat, S., Naeem, M. A., Khan, S. N., Husnain, T., Riazuddin, S., Akram, J. and Riazuddin, S. A. (2016). A spectrum of CYP1B1 mutations associated with primary congenital glaucoma in families of Pakistani descent. Hum. Genome Var. 3: 16021. PMID: 27508083. IF: 1; SJR: Q3.
  • Ullah, I., Kabir, F., Iqbal, M., Gottsch, C. B., Naeem, M. A., Assir, M. Z., Khan, S. N., Akram, J., Riazuddin, S., Ayyagari, R., Hejtmancik, J. F. and Riazuddin, S. A. (2016). Pathogenic mutations in TULP1 responsible for retinitis pigmentosa identified in consanguineous familial cases. Mol. Vis. 22: 797-815. PMID: 27440997. IF: 2.2; SJR: Q2.
  • Jiao, X., Kabir, F., Irum, B., Khan, A. O., Wang, Q., Li, D., Khan, A. A., Husnain, T., Akram, J., Riazuddin, S., Hejtmancik, J. F. and Riazuddin, S. A. (2016). A Common Ancestral Mutation in CRYBB3 Identified in Multiple Consanguineous Families with Congenital Cataracts. PLoS. One. 11(6): e0157005. PMID: 27326458. IF: 2.9; SJR: Q1.
  • Kabir, F., Ullah, I., Ali, S., Gottsch, A. D., Naeem, M. A., Assir, M. Z., Khan, S. N., Akram, J., Riazuddin, S., Ayyagari, R., Hejtmancik, J. F. and Riazuddin, S. A. (2016). Loss of function mutations in RP1 are responsible for retinitis pigmentosa in consanguineous familial cases. Mol. Vis. 22: 610-625. PMID: 27307693. IF: 2.2; SJR: Q2.
  • Khan, S. Y., Vasanth, S., Kabir, F., Gottsch, J. D., Khan, A. O., Chaerkady, R., Lee, M. C., Leitch, C. C., Ma, Z., Laux, J., Villasmil, R., Khan, S. N., Riazuddin, S., Akram, J., Cole, R. N., Talbot, C. C., Pourmand, N., Zaghloul, N. A., Hejtmancik, J. F. and Riazuddin, S. A. (2016). FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1. Nat. Commun. 7: 10953. PMID: 27218149. IF: 14.7; SJR: Q1.
  • Jiao, X., Khan, S. Y., Irum, B., Khan, A. O., Wang, Q., Kabir, F., Khan, A. A., Husnain, T., Akram, J., Riazuddin, S., Hejtmancik, J. F. and Riazuddin, S. A. (2015). Missense Mutations in CRYAB Are Liable for Recessive Congenital Cataracts. PLoS. One. 10(9): e0137973. PMID: 26402864. IF: 2.9; SJR: Q1.
  • Kabir, F., Naz, S., Riazuddin, S. A., Naeem, M. A., Khan, S. N., Husnain, T., Akram, J., Sieving, P. A., Hejtmancik, J. F. and Riazuddin, S. (2013). Novel mutations in RPE65 identified in consanguineous Pakistani families with retinal dystrophy. Mol. Vis. 19: 1554-1564. PMID: 23878505. IF: 2.2; SJR: Q2.
  • Riaz, M., Idrees, M., Kanwal, H. and Kabir, F. (2011). An overview of triple infection with hepatitis B, C and D viruses. Virol. J. 8: 368. PMID: 21791115. IF: 4; SJR: Q2.
  • Kabir, M. F., Rahman, M. S., Jamal, A., Rahman, M. and Khalekuzzaman, M. (2013). Multiple shoot regeneration in Dendrobium fimbriatum hook an ornamental orchid. J. Anim. Plant Sci. 23(4): 1140-1145.
  • Shirin, F., Hossain, M., Kabir, M. F., Roy, M. and Sarker, S. R. (2007). Callus Induction and Plant Regeneration from Internodal and Leaf Explants of Four Potato (Solanum tuberosum L.) Cultivars. World J. Agric. Sci. 3(1): 01-06. “